Through a literature review of the attitudes of clinical medical staff towards patients with non-suicidal self-injury at home and abroad in recent years, this paper aims to understand the attitudes of medical workers towards patients with self-injury and their influencing factors, and explore possible improvement measures. The results found that medical staff had negative attribution and stigmatization towards self-injury when caring for patients with self-injury, accompanied by emotional experiences such as anxiety, depression, and powerlessness, which might lead to a tendency to avoid care and weaken pain. The main factors influencing the attitude of medical staff were education and work experience, medical environment, and the behavioral responses of patients. In the future, measures such as strengthening the education and training of medical staff, establishing a mental health liaison group, and spatial reconstruction of the consultation room can be taken to optimize the care and attitude of medical staff towards patients with self-injury, and provide a supportive treatment environment for patients with self-injury.