"cultivating first-class innovative talents, producing first-class scientific research achievements" and improving "the level of teaching, scientific research and social service" are the important purposes of creating "double first-class" colleges and universities. From the perspective of improving undergraduate scientific research literacy, this paper expounds the practice and Enlightenment of teaching research interaction strategy in the construction of pharmaceutical students" scientific research literacy. The "teaching research interaction" teaching method is based on the integration with the teaching of analytical chemistry curriculum group, increases the scientific research practice platform and the connotation and opportunities of enlightenment, long-term and continuous scientific research and teaching, and can effectively improve the level of students" scientific research literacy. It strengthens the continuous benefit of students in the teaching process, effectively improves the level of students" scientific research literacy, promotes discipline reform and grows both teaching and learning.