Under the background of new medical science, in order to promote the development of medicine health industry and train compound medical talents with high ethical standard, it is huge challenge for medical schools and colleges to integrate ideological and political education into the innovative and entrepreneurship education. The paper analyzed the feasibility of integrate ideological and political education into the innovative and entrepreneurship education, discussed the difficulties encountered and solutions of integrate ideological and political education into the innovative and entrepreneurship education under the background of new medicine.It can provide beneficial guidance for training compound medical innovative talents.