By analyzing the present medical university virtual simulation resources construction in construction principles, technology, resource sharing, originality, curriculum construction and the problems of funds safeguard and so on, from insisting that complement each other, not virtual construction principle, build a comprehensive,multi terminal information management, establishing characteristic, construction of long-term mechanism of university-enterprise cooperation, To create a multi-level and three-dimensional sharing mode, to create a complementary and progressive experimental teaching system, and to improve the input guarantee system with prominent focus and multiple measures, etc., the paper provides a reference for the construction of virtual simulation resources in medical colleges and universities.